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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK15
All Species:
17.58
Human Site:
T273
Identified Species:
38.67
UniProt:
Q8TD08
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD08
NP_620590.2
544
59832
T273
D
A
L
L
P
P
D
T
S
P
E
A
L
D
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539201
559
60934
T274
D
T
L
L
P
P
D
T
P
P
E
A
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y86
549
60660
T274
D
A
L
L
P
P
D
T
P
P
E
A
L
D
L
Rat
Rattus norvegicus
Q9Z2A6
547
60705
T274
D
A
L
L
P
P
D
T
P
P
E
A
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423954
600
66936
T298
E
E
I
L
P
S
S
T
P
L
P
A
L
D
L
Frog
Xenopus laevis
P26696
361
41238
D127
K
T
Q
H
L
S
N
D
H
I
C
Y
F
L
Y
Zebra Danio
Brachydanio rerio
NP_001018581
524
58806
V274
D
E
I
L
P
A
S
V
P
P
D
A
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392445
747
85295
S285
K
E
L
L
P
E
V
S
E
K
A
L
S
L
I
Nematode Worm
Caenorhab. elegans
Q11179
470
54020
T236
Q
I
E
R
I
M
N
T
I
A
K
P
S
R
A
Sea Urchin
Strong. purpuratus
XP_001203135
583
64666
P275
E
E
V
L
P
G
A
P
A
D
A
I
D
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14681
368
42674
I134
I
L
R
A
L
K
S
I
H
S
A
Q
V
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
71.5
N.A.
69.2
68.7
N.A.
N.A.
45.3
28.6
48.3
N.A.
N.A.
34.6
42.6
44.9
Protein Similarity:
100
N.A.
N.A.
77.8
N.A.
75.5
75.1
N.A.
N.A.
60
42
64.8
N.A.
N.A.
50.5
61.2
62.6
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
93.3
93.3
N.A.
N.A.
46.6
0
53.3
N.A.
N.A.
20
6.6
13.3
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
93.3
93.3
N.A.
N.A.
60
6.6
66.6
N.A.
N.A.
33.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
0
10
0
10
10
0
10
10
28
55
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
46
0
0
0
0
0
37
10
0
10
10
0
10
55
0
% D
% Glu:
19
37
10
0
0
10
0
0
10
0
37
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
19
0
0
0
0
0
10
% H
% Ile:
10
10
19
0
10
0
0
10
10
10
0
10
0
10
10
% I
% Lys:
19
0
0
0
0
10
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
10
46
73
19
0
0
0
0
10
0
10
55
28
55
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
73
37
0
10
46
46
10
10
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
19
28
10
10
10
0
0
19
0
0
% S
% Thr:
0
19
0
0
0
0
0
55
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
10
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _